This study aims to test the hypothesis that a 30-second sit-to-stand test (30-second STS) at admission can predict respiratory disease-specific daily physical activity at discharge in patients experiencing an acute exacerbation of ILD.
Inpatients with ILD who were diagnosed with acute exacerbation were included. 30-s STS was measured from a sitting position at 40 cm from the floor, with arms crossed in front of the body, and a standing position with knees fully extended, repeated for 30 seconds The CS-30 assessment was performed during the first physical therapy session after hospitalisation for acute exacerbation. Activities of Daily Living (ADL) were evaluated using the Nagasaki University Respiratory Activities of Daily Living questionnaire during the last physical therapy session before the discharge.30-s STS was measured from a sitting position at 40 cm from the floor, with arms crossed in front of the body, and a standing position with knees fully extended, repeated for 30 seconds, based on the past study. The CS-30 assessment was performed during the first physical therapy session after hospitalisation for acute exacerbation. Activities of Daily Living (ADL) were evaluated using the Nagasaki University Respiratory Activities of Daily Living questionnaire during the last physical therapy session before the discharge.
Thirty-nine patients were identified in this study. Patients showed age (mean ± SD) 76.26 ± 8.72 years, male/female: 28/11, body mass index 23.24 ± 3.29 kg/m2, KL-6 1763.47 ± 930.25 U/ml, and modified medical research council dyspnea scale (0/1/2/3/4 respectively) n=5/4/14/8/8. The mean 30-s STS was 8.97 (95%CI: 7.78 - 10.17), the mean NRADL score at discharge was 54.28 (95%CI: 46.99 - 61.57). Multiple regression analysis using initial CS30, KL-6, and BMI showed that the number of CS-30 was independently associated with NRADL at discharge (CS30: standardised coefficient (beta) = 0.75, p 0.001; KL-6: beta = -0.21, p = 0.15; BMI: beta = 0.84, p = 0.58).
Owing to the limited feasibility of sustained exercise during the acute phase due to severe hypoxia, it is particularly pertinent to identify physical performance indicators reflecting activities of daily living that are achievable in this critical setting.
The study demonstrated that 30-s STS predict respiratory disease-specific daily physical activities in patients experiencing an acute exacerbation of ILD.
acute excerbation
30-second sit-to-stand test
