ACTN 3-R577X POLYMORPHISM AND TIMING RESPONSE TO VISUAL-AUDITORY STIMULI IN TENNIS VS. NON-ATHLETES CHILDREN IN BOGOTÁ

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Alvis Gómez KM1, Campos del Cairo AT2, Arboleda H2
1Univerisidad Nacional de Colombia, Corporal Movement Department, Bogota, Colombia, 2Universidad Nacional de Colombia, Master Degree in Neuroscience, Bogota, Colombia

Background: The efficiency in the motor gesture has been related to the adequate processing of speed, and recently linked, the genetic component as a determinant element of phenotypes associated with muscular performance. The temporal processing, motor time or timing can generate temporal patterns, where the perception of sensory stimuli, become necessary predictors for adaptation from anticipatory actions of the motor response, which allow to reduce the spatial error , calibrating and orienting the body in the space, according to the requirements of corporal addressing, synchronizing the motor response to generate motor tasks with agility and dexterity. The ACTN 3 R577X gene polymorphism has been shown to be a genetic factor associated with variations in muscle performance in humans.

Purpose: To determine if there are differences in reaction times to visual and auditory stimulation in children aged 10 to 15 years in two groups, one of high performance athletes in the sport of tennis, and a group of non-athletes, and its association with the presence of the R557X polymorphism of the Actin 3 gene.

Methods: The analytical cross-sectional investigation seeks to describe the reaction times to visual and auditory stimulation in children aged 10 to 15 years in two groups: athletes and non-athletes, using a model of reaction time measurement to visual and auditory simple stimulation and a complex one from simple temporary ordering actions in a squat jump mode activity (bosco); in order to determine whether or not there are differences in the simple and complex reaction times between the groups; also a genetic analysis, to determine the phenotypic and allelic constitution of R577X of the ACTN 3 gene in the sample, which allows the analysis of the relationship between reaction times, motor time and total movement time and genetic variants of ACTN 3 Gene The assessment protocol was endorsed by the Research Ethics Committee of the Faculty of Medicine of the National University of Colombia (Act 011-162-18).

Results: It is found that the response times to auditory and visual stimuli present differences between the groups of athletic and non-athletic children. The reaction times to the visual stimuli are determinants of the effective execution of expert movement. An association is found between the response times to stimuli and the phenotypic and allelic expression of the R577X of the ACTN 3 Gene

Conclusion(s): Temporal perception and motor time approached from neurocognition and the contribution that the genetic component can provide motor behavior have been implemented for research in athletes, where the demands of the environment require coordinated motor responses and in a shorter time to generate efficiency in terms of better sports performance. Response times associated with the response of temporal perception are shown, which relate the speed and power response associated with the genetic component alpha ACTN 3.

Implications: The temporal perception and motor time approached from neurocognition and the contribution that the genetic component can provide to the motor behavior is a relevant issue in the understanding of sports performance and the functionality of the human movement.

Keywords: Timings, time perception, polymorphism ACTN3 R577X gene, α-actinin-3

Funding acknowledgements: Department of Human Body Movement of the Faculty of Medicine - Universidad Nacional de Colombia.

Topic: Sport & sports injuries; Neurology; Human movement analysis

Ethics approval required: Yes
Institution: Universidad Nacional de Colombia
Ethics committee: Faculty of Medicine- Universidad Nacional de Colomboa
Ethics number: Act 011-162-18


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