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Ogawa A.1,2, Shimizu K.3, Yamamoto T.4, Akiba T.1,2, Terayama K.1, Tuchiya A.1, Maruoka H.2, Nakagawa K.1, Shirai K.4,5
1Toho University Sakura Medical Center, Department of Rehabilitation, Sakura, Japan, 2Saitama Prefectural University, Graduate School of Health and Medical Welfare, Koshigaya, Japan, 3Toho University Sakura Medical Center, Department of Internal Medicine, Sakura, Japan, 4Toho University Sakura Medical Center, Department of Vascular Function, Sakura, Japan, 5Seijinnkai Mihama Hospital, Katori, Japan
Background: Systemic blood flow and skeletal muscle mass are important perfroming physical activity . However, it is unclear that acute effects of vascular functional stiffness due to the exercise, and the relationship between vascular functional stiffness and skeletal muscle mass.
Purpose: The aim of this study was to investigate acute effect of resistance training (RT) on vascular functional stiffness and relationship between unctional stiffness and skeletal muscle mass.
Methods: The subjects were 12 healthy male. We measured the Cardio-Ankle Vascular Index (CAVI) as vascular functional stiffness at baseline and immediately after RT, after RT 5 minutes (5min). Concurrently, we measured heart rate (HR), stroke volume (SV), cardiac output (CO) by impedance cardiography. And evaluating the skeletal muscle mass was measured the body composition by Bioelectrical Impedance Analysis (BIA). RT was right quadriceps isometric contraction exercise performed 10 times. From the results of limb skeletal muscle mass and body height to calculate the skeletal mass index (SMI).Comparisons of each parameter rest and after RT were evaluated for statistical significance using Friedman test and Steel-Dwass test. And Mann-Whitney test used comparison change of CAVI (delta CAVI) at each times on difference between right (Rt) and left (Lt) CAVI. Associations of CAVI and SMI was examined by partial correlation adjusted for age.
Results: Both Rt and Lt CAVI significantly decreased from baseline after RT (6.00 vs 5.80 p 0.01, 6.00 vs
5.80 p 0.01), and 5min had returned (5.80 vs 6.00 p 0.01, 5.70 vs 6.00 p 0.01). And there were no significant difference between Rt and Lt in the delta CAVI. Both Rt and Lt CAVI and SMI showed significantly negative correlation (r=-0.748 p 0.05, r=-0.826 p 0.05).
Conclusion(s): Increasing in peripheral blood flow caused by the isometric contraction, thereby production of nitric oxide from endothelial cells was promoted, systemically it could vascular functional stiffness was improved. Results of the present study showed that local resistance training may contribute to the improvement of systemic vascular functional stiffness.
Implications: This study was very important that to clarify the effect of exercise to vascular functional stiffness.
Funding acknowledgements: No funding
Topic: Cardiorespiratory
Ethics approval: It is approved by the ethics committee of the affiliation.
All authors, affiliations and abstracts have been published as submitted.
