Santos ALYdS1, Maciel FKdL1, Favero FM1, de Sá CDS2
1Federal São Paulo University, São Paulo, Brazil, 2São Paulo Federal University, Human Movement Science, São Paulo, Brazil
Background: The main consequence of muscular dystrophy Duchenne (DMD) is progressive muscular weakness of the muscles, which affects the trunk control and upper limb function (UULL) of patients. Accurate assessment tools are needed to determine the best therapeutic approach and monitor its effectiveness. However, there are not studies to verify trunk control in relation to the UULL function of ambulatory and non-ambulatory patients
Purpose: To verify trunk control and UULL function in patients with ambulatory and non-ambulatory DMD
Methods: The study was approved by the research ethics committee of UNIFESP, a cross-sectional observational study. The patients were selected according to a sample calculation, composed of patients diagnosed with DMD, divided into ambulatory (Vignos ≤ 6) and non-ambulatory (Vignos ≥ 7) from the Vignos score, evaluates the staging of the disease. Later, the patients were examined by the following functional scales: (1) Segmentary Assessment of Trunk Control (SATCo), evaluate trunk control; (2) Performace of Upper Limb (PUL) and (3) Jebsen Taylor Test (TJT), both assess the UULL function. The continuous variables were compared to the T test, third of TJT (3TJT) and fourth of TJT (4TJT); Mann-Whitney test, other variables. Categorical variables were compared using the chi-square test.
Results: Fifty-one patients were included, of which 21 were ambulatory and 30 were non-ambulatory. There was a statistical difference between the groups in relation to escoliosis, pain in UULL, trunk control and UULL function by PUL scale, but only in some TJT tasks. The subtest of writing and turning cards was similar between groups. The correlation was strong between the staging of the disease with UULL function (PUL scale); between the staging of the disease and trunk control, and between trunk control and UULL function (PUL scale).
Conclusion(s): The trunk control and upper limb function are different between ambulatory and non-ambulatory patients with DMD. Non-ambulatory present worse functionality, complaint of pain and presence of scoliosis
Implications: To understand the stages of disease progression and the relationship between the skills needed to maintain functional independence. Thus, rehabilitation professionals can devise appropriate and specific treatment plans for motor deficits presented by the patient. Therefore, the therapeutic approach will ensure functional independence and delay in the progression of the disease, consequently, will promote an improvement in the quality of life of this population
Keywords: Muscular Dystrophy Duchenne, Posture, Upper Extremity
Funding acknowledgements: CAPES
Purpose: To verify trunk control and UULL function in patients with ambulatory and non-ambulatory DMD
Methods: The study was approved by the research ethics committee of UNIFESP, a cross-sectional observational study. The patients were selected according to a sample calculation, composed of patients diagnosed with DMD, divided into ambulatory (Vignos ≤ 6) and non-ambulatory (Vignos ≥ 7) from the Vignos score, evaluates the staging of the disease. Later, the patients were examined by the following functional scales: (1) Segmentary Assessment of Trunk Control (SATCo), evaluate trunk control; (2) Performace of Upper Limb (PUL) and (3) Jebsen Taylor Test (TJT), both assess the UULL function. The continuous variables were compared to the T test, third of TJT (3TJT) and fourth of TJT (4TJT); Mann-Whitney test, other variables. Categorical variables were compared using the chi-square test.
Results: Fifty-one patients were included, of which 21 were ambulatory and 30 were non-ambulatory. There was a statistical difference between the groups in relation to escoliosis, pain in UULL, trunk control and UULL function by PUL scale, but only in some TJT tasks. The subtest of writing and turning cards was similar between groups. The correlation was strong between the staging of the disease with UULL function (PUL scale); between the staging of the disease and trunk control, and between trunk control and UULL function (PUL scale).
Conclusion(s): The trunk control and upper limb function are different between ambulatory and non-ambulatory patients with DMD. Non-ambulatory present worse functionality, complaint of pain and presence of scoliosis
Implications: To understand the stages of disease progression and the relationship between the skills needed to maintain functional independence. Thus, rehabilitation professionals can devise appropriate and specific treatment plans for motor deficits presented by the patient. Therefore, the therapeutic approach will ensure functional independence and delay in the progression of the disease, consequently, will promote an improvement in the quality of life of this population
Keywords: Muscular Dystrophy Duchenne, Posture, Upper Extremity
Funding acknowledgements: CAPES
Topic: Neurology
Ethics approval required: Yes
Institution: Federal São Paulo University
Ethics committee: Federal São Paulo University
Ethics number: 2252364
All authors, affiliations and abstracts have been published as submitted.
