DO PHYSICAL PERFORMANCE MEASURES PREDICT APPENDICULAR SKELETAL MUSCLE MASS AFTER 4 YEARS OF FOLLOW UP?

Guerra R1, Barbosa JF1, Gomes C1, Britto H1, Cunha SC2, Lyra C2
1Universidade Federal do Rio Grande do Norte, Fisioterapia, Natal, Brazil, 2Universidade Federal do Rio Grande do Norte, Nutrição, Natal, Brazil

Background: Disability in old age is a major public health concern due to global population aging. Abdominal obesity is related to the disability process in older adults. Sarcopenia is an important condition in older population, however due lack of accessibility of muscle mass measures this condition may remain undiagnosed in older adults. physical performance measures (such as gait speed and handgrip strength) are longitudinally associated with both obesity and disability.

Purpose: The aim of this study was to investigate which physical performance measures predict better the muscle mass in community dwelling older adults.

Methods:
Design: Prospective cohort study.

Settings: Community dwelling older adults participants from the International Mobility Aging Study (IMIAS) in Natal, Brazil.

Subjects: 402 participants aged 64-74 years who agreed to participate in 2012 were followed for 4 years. Therefore, 249 subjects completed the 4-year follow-up examination in 2016.

Methods: Muscle mass were determined (assessed only in 2016) by bioelectrical impedance analysis (BIA) from the appendicular skeletal muscle mass (ASM), that was normalized by the body mass index (BMI) in order to obtain the skeletal muscle mass index (SMI). Physical performance measures included the assessment of handgrip strength and gait speed. Also, data of age, sex, number of chronic conditions, inflammatory level and height and weight were obtained at baseline.

Results: After adjustment for age, sex, chronic conditions and inflammatory level only handgrip strength values were able to predict muscle mass 4 years later (β=0.003; p value 0.05), gait speed was not related to muscle mass.

Conclusion(s): The measurement of handgrip strength could be useful method to screening sarcopenia status in community dwelling older adults, since could indicate early who potentially should be underwent to more specific examinations of muscle mass.

Implications: The measurement of handgrip strength could be useful method to screening sarcopenia status in community dwelling older adults.

Keywords: Sarcopenia, Aging, Screening

Funding acknowledgements: University of Montreal (CR-CHUM)

Topic: Older people

Ethics approval required: Yes
Institution: Universidade Federal do Rio Grande do Norte
Ethics committee: Research Ethics Board Federal University of Rio Grande do Norte
Ethics number: 623/2011


All authors, affiliations and abstracts have been published as submitted.

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