J. Song1, M. Chen1, B. Ruan1
1Beijing Sport University, Beijing, China
Background: Cardiovascular disease is the leading cause of death worldwide, accounting for 17 million deaths worldwide each year, or one-third of all deaths. Postmenopause was independently associated with a higher risk of CVD later in life. Estrogen levels drop significantly after menopause. The protective effect of estrogen on blood vessels is weakened, the metabolism of blood sugar and blood fat is disturbed, leading to a series of symptoms such as hot flashes, palpitation and even menopause syndrome. Not only can it disrupt personal and professional lives, but it also creates greater health care needs and more adverse outcomes, presenting a unique and difficult challenge for clinicians. High intensity interval training (HIIT) has received a lot of attention in recent years for its convenience and time-saving features. There is controversy about the effect of HIIT on cardiovascular function in postmenopausal women and a review is needed to assess the effect of HIIT on cardiovascular function in postmenopausal women.
Purpose: This study aimed to meta-analyze the effects of high intensity interval training on cardiovascular function in postmenopausal women, which can help clinicians to establish safe HIIT exercise prescriptions. And we can help postmenopausal women to actively respond to their changes in health.
Methods: A systematic literature search was conducted in PubMed, Web of Science, Cochrane and Embase, for up to 1 January 2023. Studies were included if they included postmenopausal women, examined the effects of HIIT on at least one measure of HRrest, blood pressure, blood lipids and glucose, and was Randomized controlled trial. Studies were excluded if they were not English articles, subjects had cancer or metabolic diseases, or didn’t have extractable data. Investigators independently assessed methodologic quality using the PEDro Scale. Preintervention and postintervention sample sizes, means, and standard deviations of PROs were extracted.
Results:A total of 7 studies that were included in the analysis. The mean quality score obtained after evaluation of each trial included in our meta-analysis was 6.29. Most of the studies were of high quality, having a score above 7 points. HIIT can decrease HRrest of postmenopausal women(MD=-3.02, CI:-5.73 to -0.32, p=0.93, I=0), and increase HDL(MD=0.19, CI: 0.03 to 0.35, p=0.77, I2=0). HIIT can’t improve SBP(MD= 4.63, 95% CI: 0.04 to 9.22, p=0.89, I2 = 0%) , DBP(MD=3.20, 95% CI:0.32 to 6.09, p=0.92, I2=0%), Meta-analysis revealed overlapping 95% CI in glucose(MD=-0.03, 95% CI: -0.20 to 0.15, p=0.32, I2=1%) and blood lipids except HDL.
Conclusions: HIIT can significantly improve cardiovascular function in postmenopausal women in some ways such as HRrest, but the potential of HIIT for postmenopausal women requires further elucidation.
Implications: This study clarified the effect of HIIT on the cardiovascular function of postmenopausal women, helped women to cope with the physical changes after menopause in a healthier way of exercise, brought positive effects on active aging, and aroused the public's attention to women's health. At the same time, it could guide clinicians to formulate exercise prescriptions, and play a preventive role in the occurrence of postmenopausal CVD in women. Thus reducing the medical burden for the whole society.
Funding acknowledgements: 没有
Keywords:
High intensity interval training
Postmenopausal
Cardiovascular function
High intensity interval training
Postmenopausal
Cardiovascular function
Topics:
Health promotion & wellbeing/healthy ageing/physical activity
Older people
Cardiorespiratory
Health promotion & wellbeing/healthy ageing/physical activity
Older people
Cardiorespiratory
Did this work require ethics approval? No
Reason: This study is a systematic meta-analysis.
All authors, affiliations and abstracts have been published as submitted.
