EFFECT OF MULTIDISCIPLINARY INTERVENTIONS ON THE QUALITY OF LIFE OF PATIENTS WITH MULTIPLE SCLEROSIS: A SYSTEMATIC REVIEW

J.-A. Deray¹, H. Labao¹, J.V. Ramos¹, B.K. Dayrit¹, C. Barbosa¹, M.E. Cabal¹, D.A. Fecara¹, M.G. Mellante¹, H.C. Navarro¹, E.M. Peña¹

¹Our Lady of Fatima University, College of Physical Therapy, Quezon City, Philippines

Background: Multiple Sclerosis (MS) is an autoimmune disorder of the central nervous system (CNS). Currently, the most suggested intervention options for enhancing the quality of life in this population are those based on multidisciplinary research.

Purpose: The study aims to review published literature on the Effect of Multidisciplinary Interventions on the Quality of Life of Patients with Multiple Sclerosis to produce state-of-the-art recommendations and consistent discipline combinations for optimal holistic patient care.

Methods: The study thoroughly analyzed papers published between January 2010 and February 2022. The publications are gathered from five critical databases: Cochrane, JSTOR, PEDro, PubMed, and ScienceDirect. With Rayyan, the data is analyzed. Independent reviewers evaluate the quality of the papers included in the review using the PEDro Scale and the Cochrane Collaboration tool.

Results: The review includes ten studies with an average of 129 participants for each of the 513 identified articles. In QOL domains, multidisciplinary rehabilitation programs address limits in physical role (p = 0.016), emotional role (p = 0.010), mental wellbeing composite (p = 0.017), and cardiorespiratory fitness (p = 0.017). In addition, it improves Fatigue, as measured by the Chalder Fatigue Scale, the SF-36 vitality subscale, and Fatigue self-efficacy. Only one study found no statistically significant differences in its primary outcome. With 19 individuals, the Level of Activity improved, notably the Timed 50 Meter Walk (p = 0.014), walking speed (p = 0.034), 2- (p = 0.204), and 6-Minute Walk (p = 0.027).

Conclusions: In terms of quality of life and decrease in fatigue, multidisciplinary interventions have a remarkable impact on the activity level of MS patients. Findings suggest that Multidisciplinary interventions and other treatment combinations are best recommended in patients with MS to improve multi-components of QoL and different outcomes such as fatigue.

Implications: The study intervention focused primarily on a Multidisciplinary approach, scoping with a general intervention discipline that was considered complementary intervention dealing with improvements of HRQoL, Fatigue, and Level of Activity. Exclusion criteria are followed mainly by a study that addresses only a single discussion of a medical profession. This review focuses only on patients with multiple sclerosis.

Funding acknowledgements: None

Keywords:
Multidisciplinary Intervention
Multidisciplinary Approach
Multiple Sclerosis

Topics:
Neurology: multiple sclerosis
Neurology
Disability & rehabilitation

Did this work require ethics approval? No

Reason: the Panel action is EXEMPTION FROM ETHICAL REVIEW since the study does not involve human participants or does not impose risks to human participants