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A. Alqahtani1, V. Vennu1, S. Bindawas1
1King Saud University, Department of Rehabilitation Sciences, Riyadh, Saudi Arabia
Background: Few studies have examined the association between osteoarthritis (OA) and cardiovascular diseases (CVDs). However, no study determined factors behind the risk of CVDs in persons with or at high risk for knee OA.
Purpose: The purpose of this study is to identify the factors behind the risk of CVDs in people with or at high risk for knee OA. Identifying these factors will guide the healthcare providers in managing the risk of CVDs in people with or at high risk for knee OA.
Methods: In this cross-sectional study, we used logistic regression models to analyze the baseline data (2004—2006) from the Osteoarthritis Initiative on 4674 persons with or at high risk for knee OA.
Results: The results indicate that age 65 years and above associated significantly (p <.0001) more than twice times predictor for CVDs, such as heart attack, heart failure, and stroke. Being a male and having diabetes were more likely associated significantly (p <.050) by more than twice and one time, respectively, predictors of both heart attack and heart failure. Having depressive symptoms were more likely associated significantly (p <.0001) by more than twice times predictor of both heart failure and stroke. The odds of more than twice a heart attack was associated significantly (p <.050) with obesity. In contrast, more than once, odds of heart failure were associated significantly (p <.050) with physical inactivity.
Conclusion(s): This study identifies easily measured sociodemographic (age and male), and clinical factors, such as obesity, diabetes, depressive symptoms, and physical inactivity, as factors behind the risk of CVDs. These findings provide a rationale for further investigation of those factors behind the risk of CVDs in longitudinal studies among this population.
Implications: Since CVDs are the leading cause of mortality, it is imperative to detect the modifiable and non-modifiable factors behind CVDs in people with or at high risk for knee OA for two reasons. First, to minimize the burden of healthcare costs of treating CVDs. Second, to prevent or at least alleviate the CVDs’ secondary complications.
Funding, acknowledgements: There was no fund for this research.
Keywords: cardiovascular, osteoarthritis, heart failure
Topic: Cardiorespiratory
Did this work require ethics approval? No
Institution: N/A
Committee: N/A
Reason: This study was a secondary analysis.
All authors, affiliations and abstracts have been published as submitted.
