FATIGUE IN KIDNEY TRANSPLANT RECIPIENTS

Loureiro APC1, Lopes APdC2, Gonçalves KV2, Stresser TZ2
1Pontificia Universidade Católica do Paraná, Physical Therapy, Curitiba, Brazil, 2PUCPR, Curitiba, Brazil

Background: Fatigue is one of the most prominent and debilitating symptoms among renal patients that decreases the ability to function and carry out daily activities.

Purpose: The purpose of this study was to assess and compare functional capacity (FC) and fatigue perception between patients submitted to renal transplantation in acute and chronic phase.

Methods: 68 kidney transplant recipients were divided into acute (AG) and chronic group (CG). The main outcome measures for functional capacity was the 6 Minute Walk Test (6MWT), while fatigue perception was assessed using the Fatigue Severity Scale (FSS).

Results: Ttwenty three patients in AG (mean age 47, 0 ±13, 5 years, 10.2 ±5.5 days post-transplant) and forty five patients in CG (mean age 47, 6±13 years, 42,9 ±37,3 months post-transplant) were included in the study. Distance walked in 6 min was significantly shorter in patients in AG than patients in CG (293, 3± 92 versus 344,3 ± 96 m, p 0,04). We found that all patients reported fatigue, however, fatigue perception was similar between groups (32, 7±16,4 versus 28,0±16,8, p 0,20). There was no correlation between the distance in the walk test and fatigue perception neither in the AG (r = -0,36, p   0,84) nor in the CG (r=-0,58, p 0,70).

Conclusion(s): The causes of fatigue in kidney transplant recipients seem not to be just physical but multifactorial

Implications: Clinical recognition of the complexity of fatigue may create individualized treatment approaches for renal transplant patients.

Keywords: Kidney transplant, Fatigue, Functional capacity

Funding acknowledgements: This work received no funding.
We would like to thank the renal transplant service at Cajuru Hospital, Curitiba- Brazil

Topic: Professional practice: other; Outcome measurement

Ethics approval required: Yes
Institution: Pontifícia Universidade Católica do Paraná
Ethics committee: CEP- PUCPR
Ethics number: 1867197


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