LIPUS (LOW INTENSITY PULSED ULTRASOUND) IMPROVES PATIENT OUTCOME, INCREASES OSTEOGENESIS AND NEOVASCULARIZATION IN AVN HIP AFTER AUTOLOGOUS ADULT LIVE CULTURED OSTEOBLASTS

T. Parey¹, S. Dikshith², K.J. Reddy², M. Ventakata Ramanaiah¹, K. Sunil Depak¹, S.S. Neerudu³, D. Parey⁴

¹Apollo Health City, Physiotherapy and Rehabilitation, Hyderabad, India, ²Apollo Health City, Orthopaedics, Hyderabad, India, ³THF International Home Health Care Pvt Ltd, Physiotherapy and Rehabilitation, Hyderabad, India, ⁴CHIREC, IBDP, Hyderabad, India

Background: Long COVID19 is known to affect different body systems, one being AVN. This sequel has been documented in several countries. Autologous cultured osteoblast implantation is found to be one of the best treatment modalities for post COVID 19 AVN hips. Moreover, LIPUS in post surgery AVN patients is found to be very effective in osteogenesis.

Purpose: To evaluate the effect of augmentation of LIPUS to autologous cultured osteoblast implantation in AVN hip patients.

Methods: A total of 90 patients aged between 25 to 50 years who underwent autologous adult live cultured osteoblasts were included in the study. Patients were randomly allocated into a LIPUS group and a non-LIPUS group. LIPUS therapy was given to the patients in LIPUS group whose results were evaluated at the end of every 6 months for 1 year.

Results: Of the 90 patients, 45 patients were in the LIPUS group and 45 patients in the non-LIPUS group. There was a significant difference in pain scores and improvement in the Range of Movement (ROM) in the LIPUS group as compared to the non-LIPUS group at the end of every 6 months for a year. Furthermore, a significant improvement in new bone formation was observed in the LIPUS group when compared to the non-LIPUS group at the end of one year.

Conclusions: In conclusion, LIPUS therapy in patients with Long COVID 19 when combined with Autologous Adult Live Cultured Osteoblasts for AVN hip, significantly decreases pain, improves ROM and increases new bone formation. LIPUS therapy when augmented with surgery improves final outcome of the patients.

Implications: LIPUS therapy after autologous cultured osteoblast implantation is a novel treatment approach in improving functional outcome, osteogenesis and neovascularization of post Long COVID 19 AVN hips compared to traditional physiotherapy.

Funding acknowledgements: self

Keywords:
LIPUS
Long COVID 19
AVN

Topics:
COVID-19

Did this work require ethics approval? Yes

Institution: Apollo Health City

Committee: Clinical Ethics Committee

Ethics number: AHC 54464