File
Büsching G1, Crook S2, Schultz K3, Lehbert N3, Jelusic D3, Keusch S4, Wittmann M3, Schuler M5, Radtke T2, Frey M1, Turk A4, Puhan MA2, Frei A2
1Klinik Barmelweid AG, Barmelweid, Switzerland, 2University of Zürich, Epidemiology, Biostatistics and Prevention Institute, Dept of Epidemiology, Zürich, Switzerland, 3Centre for Rehabilitation, Pulmonology and Orthopaedics, Klinik Bad Reichenhall, Bad Reichenhall, Germany, 4Zürcher RehaZentrum Wald, Wald, Switzerland, 5University of Würzburg, Dept of Medical Psychology, MedicalSociology and Rehabilitation Sciences, Würzburg, Germany
Background: Commonly used and well-established exercise capacity tests in chronic obstructive pulmonary disease (COPD), such as the 6-min walk test (6MWT) and incremental shuttle walk test are not often assessed in inpatient, specialist outpatient or primary care settings due to the time, space and resources required to conduct them. Since these settings are where most patients with COPD are seen by practitioners, many patients are not able to have their exercise capacity assessed.
Purpose: Our aim was to comprehensively validate the 1-min sit-to-stand (STS) test in chronic
obstructive pulmonary disease (COPD) patients and explore the physiological response to the test.
Methods: We used data from two longitudinal studies of patients with COPD who completed inpatient pulmonary rehabilitation programmes. We collected 1-min STS test, 6-min walk test (6MWT), health-related quality of life, dyspnoea and exercise cardiorespiratory data at admission and discharge. We assessed the learning effect, test-retest reliability, construct validity, responsiveness and minimal important difference of the 1-min STS test.
Results: In both studies (n=52 and n=203) the 1-min STS test was strongly correlated with the 6MWT at admission (r=0.59 and 0.64, respectively) and discharge (r=0.67 and 0.68, respectively). Intraclass correlation coefficients (95% CI) between 1-min STS tests were 0.93 (0.83-0.97) for learning effect and 0.99 (0.97-1.00) for reliability. Standardised response means (95% CI) were 0.87 (0.58-1.16) and 0.91 (0.78-1.07). The estimated minimal important difference was three repetitions. End-exercise Oxygen consumption, carbon dioxide output, ventilation, breathing frequency and heart rate were similar in the 1-min STS test and 6MWT.
Conclusion(s): The 1-min STS test is a reliable, valid and responsive test for measuring functional exercise capacity in patients with COPD and elicited a physiological response comparable to that of the 6MWT.
Implications: The 1-min STS test is suitable for use in clinical practice and research settings when traditional tests are not practical.
Keywords: Pulmonary Rehabilitation, 1 min Sit to Stand Test, Validation
Funding acknowledgements: The Verein Lunge Zurich foundation (STAND-UP) and the Deutsche Rentenversicherung Bayern Süd (RIMTCORE)
Purpose: Our aim was to comprehensively validate the 1-min sit-to-stand (STS) test in chronic
obstructive pulmonary disease (COPD) patients and explore the physiological response to the test.
Methods: We used data from two longitudinal studies of patients with COPD who completed inpatient pulmonary rehabilitation programmes. We collected 1-min STS test, 6-min walk test (6MWT), health-related quality of life, dyspnoea and exercise cardiorespiratory data at admission and discharge. We assessed the learning effect, test-retest reliability, construct validity, responsiveness and minimal important difference of the 1-min STS test.
Results: In both studies (n=52 and n=203) the 1-min STS test was strongly correlated with the 6MWT at admission (r=0.59 and 0.64, respectively) and discharge (r=0.67 and 0.68, respectively). Intraclass correlation coefficients (95% CI) between 1-min STS tests were 0.93 (0.83-0.97) for learning effect and 0.99 (0.97-1.00) for reliability. Standardised response means (95% CI) were 0.87 (0.58-1.16) and 0.91 (0.78-1.07). The estimated minimal important difference was three repetitions. End-exercise Oxygen consumption, carbon dioxide output, ventilation, breathing frequency and heart rate were similar in the 1-min STS test and 6MWT.
Conclusion(s): The 1-min STS test is a reliable, valid and responsive test for measuring functional exercise capacity in patients with COPD and elicited a physiological response comparable to that of the 6MWT.
Implications: The 1-min STS test is suitable for use in clinical practice and research settings when traditional tests are not practical.
Keywords: Pulmonary Rehabilitation, 1 min Sit to Stand Test, Validation
Funding acknowledgements: The Verein Lunge Zurich foundation (STAND-UP) and the Deutsche Rentenversicherung Bayern Süd (RIMTCORE)
Topic: Cardiorespiratory; Outcome measurement; Disability & rehabilitation
Ethics approval required: Yes
Institution: Swiss Ehtics
Ethics committee: Kantonale Ethikkommission Zürich, Nordwest- und Zentralschweiz,Bayerischen Landesärztekammer
Ethics number: Zürich (2014-0614), Nordwest- und Zentralschweiz (2015-095) Bayerischen Landesärztekammer (12107)
All authors, affiliations and abstracts have been published as submitted.
