Muscle atrophy in malnutrition acute stroke patients is a factor that causes a decrease in physical function and ADL.

Junya Yamanoi
Purpose:

　The purpose of this study was to clarify the influence of muscle atrophy of malnourished acute stroke patients on PF and ADL.


Methods:

 This is a multicenter study. The inclusion criteria were patients aged 65 years or older who were admitted to an acute care ward between May 30, 2022 and May 29, 2024. The study involved 220 subjects. Malnourished acute stroke patients was determined by assessing the Global Leadership Initiative on Malnutrition upon admission. For lower limb muscle atrophy, muscle thickness (QMT), pennation angle (QPA) and echo intensity (QEI) of the quadriceps of the affected and unaffected sides were measured using a B-mode ultrasound imaging device (SONON 300L). PF and ADL were evaluated for Functional Independence Measure (FIM） and Short Physical Performance Battery (SPPB), respectively. All evaluation items were evaluated at admission and discharge. Statistical analysis used stepwise multiple regression analysis to identify factors individually associated with FIM and SPPB. QMT, QPA and QEI were set as the independent variables. Statistical significance was accepted as p0.05.


Results:

　FIM and SPPB at admission and discharge were significantly independently associated with the QMT, QPA and QEI of the affected and unaffected sides(QMT and QPA β>0.43 QEI β-0.45).


Conclusion(s):

 It was suggested that muscle atrophy of malnourished acute stroke patients  is a factor that decreases ADL and PF. 


Implications:

 Based on the above, it is necessary to assess atrophy in malnourished acute stroke patients  and in some cases, intervention is required. 


Funding acknowledgements:
The authors declare no conflicts of interest associated with this manuscript.
Keywords:
malnutrition
stroke
muscle atrophy
Primary topic:
Neurology: stroke
Second topic:
Musculoskeletal: lower limb
Third topic:
Older people
Did this work require ethics approval?:
Yes
Name the institution and ethics committee that approved your work:
We conducted with the approval of the ethics committee of Hattori Hospital.
Provide the ethics approval number:
201811
Has any of this material been/due to be published or presented at another national or international conference prior to the World Physiotherapy Congress 2025?:
No

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