PREVALENCE AND PATTERN OF MUSCULOSKELETAL COMPLICATIONS OF SICKLE CELL PAEDIATRIC CHILDREN IN NORTHERN NIGERIA: A TEN-YEAR RETROSPECTIVE STUDY

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Mayana KI1,2, Dantata AB2, Akindele M2
1University of Salford, Rehabilitation, Salford, United Kingdom, 2Bayero University Kano, Physiotherapy, Kano, Nigeria

Background: The prevalence of Sickle cell in increasing in developing countries due to lack of awareness and other socio-cultural challenges. The hereditary blood disorder caused by an abnormality in oxygen-carrying protein hemoglobin found in red blood cells presents various types of clinical manifestations including musculoskeletal manifestations. Musculoskeletal complications of SCD result from vessel occlusion, leading to tissue ischemia, infarction, progressive and organ damage, and bone marrow hyperplasia. This study aimed to find out the prevalence and pattern of musculoskeletal complications in pediatric sickle cell children.

Purpose: This study aimed to find out the prevalence and pattern of musculoskeletal complications in pediatric sickle cell children.

Methods: A retrospective descriptive study of hospital-based records using patients case folders. Ten years case notes (2005-2015) of SCA patients were reviewed in three hospitals in Kano, North Western Nigeria. Information on age, gender, type of musculoskeletal complication, Joint affected and the annual distribution of the complications were recorded.

Results: Records shows a total of 500 case folders in which patients presented with musculoskeletal complications. Results revealed 280(56%) males and 220(44%) females. The musculoskeletal complications were found to be acute osteomyelitis (64%), chronic osteomyelitis (30.4%), Leg ulcer (2.2%), septic arthritis (1.8%) and Juvenile ankylosing spondylitis (0.2%). The pattern of musculoskeletal complications in children was found to be 227(45.4%) among 0-5years and 273(54.6%) among 6-12years. The lower limbs were found to be commonly affected 349(69.9%).

Conclusion(s): The study found acute osteomyelitis as the most common musculoskeletal disorder representing (64%) of the disorders, and thus, identified as children advance in age, there was an increase in the development of musculoskeletal complications and the lower limb was found to be most commonly affected.

Implications: This study shows a high prevalence of the musculoskeletal disorder in sickle cell children. This has caused a huge burden on the children and caregivers. More attention should be given to awareness of prevention of the disease.

Keywords: sickle cell, prevelance, nigeria

Funding acknowledgements: This study was not funded.

Topic: Paediatrics; Musculoskeletal

Ethics approval required: Yes
Institution: Aminu Kano Teaching Hospital
Ethics committee: Ethics committee of Aminu Kano Teaching Hospital
Ethics number: AKTH- PHY- ECT- 71/15


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