Published post-operative anterior cruciate ligament reconstruction rehabilitation programs are not reproducible in clinical practice: a scoping review

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Giuseppe Filardo, Chad Cook, Nicol Van Dyk, Giacomo Severini, Catherine Blake, Eamonn Delahunt, Sebastiano Nutarelli
Purpose:

Via a scoping review, we evaluated the clinical reproducibility of rehabilitation programs in published peer-reviewed articles describing primary ACL-R.

Methods:

We performed a systematic literature search, on 8 July 2024, using the following medical databases: MEDLINE via PubMed, Web of Science, Cochrane Library, and Scopus. Following title, abstract, and full-text screening, 250 studies including 29,216 individuals were identified that satisfied our pre-specified inclusion criteria. Before data extraction, 2 authors (SN, ED) developed the preliminary domains to categorize the descriptions of the post-operative rehabilitation programs. One author (SN) adapted these domains based on the emerging characteristics of the extracted data observed during the data charting process. Additionally, the post-operative rehabilitation programs described in each study were evaluated using the template for intervention description and replication (TIDieR) checklist (12 items) to determine their clinical reproducibility; a score of 0 (minimum) to 12 (maximum) was assigned to each study. A median TIDier score was determined for each domain used to categorize the descriptions of the rehabilitation programs. The following scores were assigned to classify the clinical reproducibility of the post-operative rehabilitation programs: TIDier score 0-4 = not clear; 5-8 = somewhat clear; 9-12 = clear.

Results:

At the end of the data charting process, 27 domains were included to categorize the descriptions of the post-operative rehabilitation programs. ACL-R via arthroscopy was the most performed surgical procedure (79%) and bone-patellar-tendon-bone graft the most frequently used graft type (45%). Concurrent lesions to ACL rupture were reported in 31% of the studies; meniscus lesions were the most common concomitant injury (61%). Almost half of the studies did not report the presence/absence of any concomitant intra-articular injuries. Across the included studies, there was a substantial degree of heterogeneity in the thoroughness of reporting of ACL-R rehabilitation programs. The highest number of domains described in any study was 20, but only one study (0.4%) achieved this level of reporting. Forty studies (16%) only included 1 domain when describing their ACL-R rehabilitation program. An average of 75% of studies per domain reported whether the decision-making on interventions was time- or criteria-based, with 89.5% being the first. The domain’s reproducibility in clinical practice, rated with the median of the TIDieRs of all the studies concurring to each domain, resulted unclear (mcTIDieR min-max score = 6.24-7.23/12). Studies often lacked proper detail on the delivered post-operative PT interventions and/or progression parameters.

Conclusion(s):

Post-primary ACL-R rehabilitation programs in published peer-reviewed articles are largely clinically reproducible.

Implications:

This study's findings can lead clinicians to carefully evaluate the published literature describing rehabilitation programs for patients after ACL-R.

Funding acknowledgements:
No financial support for this research project was received.
Keywords:
anterior cruciate ligament
rehabilitation
physical therapy
Primary topic:
Orthopaedics
Second topic:
Sport and sports injuries
Third topic:
Musculoskeletal: lower limb
Did this work require ethics approval?:
No
Has any of this material been/due to be published or presented at another national or international conference prior to the World Physiotherapy Congress 2025?:
Yes

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