Relationship between blood flow velocity in the anterior humeral circumflex artery and pain in patients with Frozen Shoulder

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Masato Kako, Atsuaki Suzuki, Hiroshi Nakahara, Hiroaki Kuwahara, Tadahiro Sakai, Atsushi Suzuki
Purpose:

This study aims to determine the association between the blood flow velocity in the AHCA and pain in patients with FS.

Methods:

Twenty patients with FS were included in the study. The affected AHCA measurements of the subjects were identified in color Doppler mode using an ultrasound imaging system with a 12 MHz linear probe. The peak systolic velocity (PSV) of the AHCA was measured using pulsed Doppler mode. Rest and night pain were assessed using the Visual Analog Scale (VAS). Statistical analysis examined the correlation between the blood flow velocity in AHCA and VAS scores using Spearman's rank correlation coefficient. To calculate the cut-off values for rest and night pain in patients with FS, ROC analysis was performed, defining the pain group as those with a VAS of 30 mm or more and the no-pain group as those with a VAS of 30 mm or less. The calculated items included cut-off value, area under the curve (AUC), and 95% confidence interval (CI).

Results:

The correlation between the blood flow velocity in AHCA and rest pain was, a significant moderate positive correlation (r = 0.59, p = 0.006). The correlation between the blood flow velocity in AHCA and night pain was also a significant moderate positive correlation (r = 0.76, p 0.001). The cut-off values for the blood flow velocity in AHCA were 13.4 cm/s (AUC: 0.92, 95% CI: 0.79–1.00) for resting pain and 13.4 cm/s (AUC: 0.93, 95% CI: 0.82–1.00) for night pain.

Conclusion(s):

The mechanisms underlying increased the blood flow velocity have been linked to blood supply to abnormal vessels and synovitis, which may reflect the pathogenesis of synovitis and angiogenesis in FS.

Implications:

The use of the blood flow velocity in AHCA as an aid in physiotherapy assessment would enable physiotherapy for FS to be based on objective indicators. 

Funding acknowledgements:
In this study, we have not received funding.
Keywords:
Frozen Shoulder
Ultrasonography
AHCA
Primary topic:
Musculoskeletal: upper limb
Second topic:
Musculoskeletal
Third topic:
Disability and rehabilitation
Did this work require ethics approval?:
Yes
Name the institution and ethics committee that approved your work:
Toyota Memorial Hospital Clinical Ethics Committee
Provide the ethics approval number:
R454
Has any of this material been/due to be published or presented at another national or international conference prior to the World Physiotherapy Congress 2025?:
No

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