The purpose of this study is to investigate the relationship between the Qmci-J and MoCA-J, which has high sensitivity and specificity for detecting MCI, in order to promote the Qmci-J in Japanese clinical settings.
The subjects of this study were community-dwelling elderly in Omuta City, Fukuoka Prefecture, who participated in exercise classes and other programs. The study was explained to them and 93 people (mean age 79.5 ± 6.0 years, 21 men and 72 women) participated in this study. Cognitive function tests measured the MMSE-J, Qmci-J, and MoCA-J. Based on the MMSE-J results, participants were classified into three groups; (MMSE-J: 28 points or higher were normal, 24-27 points were suspected MCI, and 23 points or lower were suspected dementia). Statistical analysis was performed to examine the correlation between each test and to compare scores among the three groups. The time required between each test was also compared.
Participants in this study (n = 93) included 8 people(8.6%) with suspected dementia, 26 people (28.0%) with suspected MCI, and 59 people (63.4%) with normal cognitive function. The Qmci-J had a significant moderate positive correlation with the MMSE-J and MoCA-J(MMSE-J:r=0.587,p<0.001)(MoCA-J:r=0.673,p<0.001). The Qmci-J was significantly different among all three groups in the comparison of normal, suspected MCI, and suspected dementia (normal: 64.7 ± 9.6 points, suspected MCI: 59.2 ± 8.9 points, suspected dementia: 29.8 ± 13.1 points). The time required for each of the three tests was significantly shorter for the Qmci-J compared to MMSE-J and MoCA-J (MMSE-J:467.9 ± 126.3s, Qmci-J:402.0 ± 54.3s, MoCA-J:866.9 ± 157.1s).
The Qmci-J showed a moderately significant positive correlation with the MMSE-J and MoCA-J, and there were significant differences in all comparisons between the three groups based on cognitive function. The Qmci-J screen can be completed in a short time and may be a useful screening tool for early identification of the elderly at risk of cognitive impairment in busy clinical settings. Further research is needed.
This research may contribute to the dissemination of the Qmci-J in Japan. Furthermore, in the future, early detection of cognitive decline among the elderly living in the community and appropriate intervention may lead to dementia prevention.
Dementia prevention
Short cognitive impairment screen