A Systematic Review and Meta-Analysis of Exercise Beneficial for Locomotion in Community-Dwelling Elderly with Sarcopenia

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seonghyeok song, gushik Kim
Purpose:

Analyze randomized controlled trials (RCTs) and investigate the impacts of locomotion in individuals with sarcopenia. Both qualitative and quantitative analyses were conducted, facilitating a robust comparison and evaluation of exercise effects. By synthesizing the existing evidence, study aims to provide a comprehensive understanding of the effects of exercise on locomotion in sarcopenia and contribute to the development of effective exercise interventions targeting this population.

Methods:

we aimed to perform qualitative and quantitative analyses by synthesizing randomized controlled trials (RCTs) that evaluated exercises that affected locomotion in patients with sarcopenia. The RCTs were retrieved in April 2023 from three international electronic databases (Embase, MEDLINE, and PubMed). RCTs published after 2013 were compared with a control group that did not include exercise. Qualitative and quantitative analyses were performed on the identified studies using RevMan 5.4 and risk of bias assessment provided by Cochrane. RCTs involving 594 patients with sarcopenia were included in this study.


Results:

 The analysis model was synthesized as a random effects model, and the standard mean Citation: Song, S.; Kim, G.; Kim, H. A Systematic Review and Meta-Analysis of Exercise Beneficial for Locomotion in Community-Dwelling Elderly People with Sarcopenia. J. Funct. Morphol. Kinesiol. 2023, 8, 92. https://doi.org/10.3390/ jfmk8030092 Academic Editor: Giuseppe Musumeci Received: 24 May 2023 Revised: 20 June 2023 Accepted: 26 June 2023 Published: 29 June 2023 Copyright: © 2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/ 4.0/). difference (SMD) was used as the effect measure. Exercise interventions were found to not change muscle mass in individuals with sarcopenia (SMD = 0.04; 95% CI: 0.15 to 0.22). However, they had positive effects on lower extremity muscle strength (SMD = 0.34; 95% CI: 0.02 to 0.66) and walking speed (SMD =0.42; 95% CI: 0.11 to 0.72). 

Conclusion(s):

For community-dwelling elderly people with sarcopenia, exercise intervention did not lead to an increase in reduced muscle mass, but it brought positive improvements in lower extremity strength and gait speed to improve locomotion.

Implications:

Recently, we aim to predict the diagnosis of sarcopenia early to prevent the decrease in mortality due to the increase in the elderly population and to create basic data that can prevent and predict sarcopenia. In addition, by diagnosing sarcopenia early, it is thought that physical therapy and exercise approaches will prevent sarcopenia in the elderly and affect mortality.

Funding acknowledgements:
This study received no external funding.
Keywords:
aging
sarcopenia
physiotherpy
Primary topic:
Health promotion and wellbeing/healthy ageing/physical activity
Second topic:
Disability and rehabilitation
Third topic:
Primary health care
Did this work require ethics approval?:
Yes
Name the institution and ethics committee that approved your work:
Adhering to the guidelines of the Preferred Reporting Items for Systematic Reviews andMeta-Analysis (PRISMA),ourstudywasmeticulouslyprepared. systematic reviews (PROSPERO)
Provide the ethics approval number:
CRD42023391773
Has any of this material been/due to be published or presented at another national or international conference prior to the World Physiotherapy Congress 2025?:
No

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