da Silva Frônio J1, Madeira Zancanelli A2, Mendonça Bárbara Dos Reis Garcia G1, Ferreira Jaques Da Cruz Júnior C1, Silva De Carvalho Chagas P1, Helena Cerqueira Mármora C1
1Federal University of Juiz de Fora, Faculty of Physical Therapy, Juiz de Fora, Brazil, 2Federal University of Juiz de Fora, Juiz de Fora, Brazil
Background: In November 2015 the Ministry of health issues the first epidemiological bulletin on microcephaly related to Zika Virus and after registration of many cases in several Brazilians States, the Ministry of health declares Public Health Emergency. As a new condition it is necessary a closer surveillance at how the development occurs in infants with confirmed Zika Virus infection during the pregnancy period, including language acquisitions.
Purpose: To describe the development of language in the first 20 months of life of Brazilians infants that were born from a pregnancy where there was a confirmed Zika Virus infection.
Methods: This is a longitudinal, prospective, observational study that evaluated 14 infants from 8 to 20 months old, born in Juiz de Fora, Minas Gerais, Brazil, with confirmed Zika Virus infection during gestational period. For assessment of the language, Language Bayley Scale - Third Edition (Bayley III) was used.
Results: Of the 14 infants, 57.1% were female and 42.9% male, and three of them had congenital Zika Virus syndrome. Seven infants were assessed between 8 and 12 months, and 2 (28.57%) of them showed delays in language, being one in expressive language. Between 13 and 16 months, 10 infants were evaluated and five of them (50%) showed language delays according to Bayley Scale, with four resulting exclusively from the receptive language subscale. Twelve participants were evaluated between 17 and 20 months, three (25%) of them showed developmental delay in the two subscales of Language Bayley Scales (receptive and expressive). Considering the three ages groups, 7 (50%) of the 14 infants assessed showed language delays during the period of the study.
Conclusion(s): Gestational infection by Zika Virus affected language development between 8 and 20 months of age of the participants, especially the receptive language, even in some infants without congenital Zika Virus syndrome.
Implications: The results reinforce the importance of the surveillance of the infants and preschoolers development that were exposed to Zika Virus Infection during the pregnancy period, even in the absence at birth of the Microcephaly or others malformations that imply in the diagnostic of congenital Zika Virus syndrome.
Keywords: Zika Virus infection, Child development, Language
Funding acknowledgements: Thanks to FAPEMIG and PROPP/UFJF
Purpose: To describe the development of language in the first 20 months of life of Brazilians infants that were born from a pregnancy where there was a confirmed Zika Virus infection.
Methods: This is a longitudinal, prospective, observational study that evaluated 14 infants from 8 to 20 months old, born in Juiz de Fora, Minas Gerais, Brazil, with confirmed Zika Virus infection during gestational period. For assessment of the language, Language Bayley Scale - Third Edition (Bayley III) was used.
Results: Of the 14 infants, 57.1% were female and 42.9% male, and three of them had congenital Zika Virus syndrome. Seven infants were assessed between 8 and 12 months, and 2 (28.57%) of them showed delays in language, being one in expressive language. Between 13 and 16 months, 10 infants were evaluated and five of them (50%) showed language delays according to Bayley Scale, with four resulting exclusively from the receptive language subscale. Twelve participants were evaluated between 17 and 20 months, three (25%) of them showed developmental delay in the two subscales of Language Bayley Scales (receptive and expressive). Considering the three ages groups, 7 (50%) of the 14 infants assessed showed language delays during the period of the study.
Conclusion(s): Gestational infection by Zika Virus affected language development between 8 and 20 months of age of the participants, especially the receptive language, even in some infants without congenital Zika Virus syndrome.
Implications: The results reinforce the importance of the surveillance of the infants and preschoolers development that were exposed to Zika Virus Infection during the pregnancy period, even in the absence at birth of the Microcephaly or others malformations that imply in the diagnostic of congenital Zika Virus syndrome.
Keywords: Zika Virus infection, Child development, Language
Funding acknowledgements: Thanks to FAPEMIG and PROPP/UFJF
Topic: Paediatrics
Ethics approval required: Yes
Institution: Federal University of Juiz de Fora- UFJF
Ethics committee: Ethics in Research Committee of the UFJF
Ethics number: Approved on April, 05, 2017, protocol. n° 2.001.169
All authors, affiliations and abstracts have been published as submitted.
